Bovine monoclonal antibody to bovine leukemia virus glycoprotein GP51 from bovine-murine hybridoma.
نویسندگان
چکیده
منابع مشابه
Molecular dissection of the bovine leukemia virus envelope glycoprotein (BLV gp51) by a monoclonal antibody study.
Neoplasms of the lymphatic tissue in the bovine species can be classified into two major types according to clinical and epidemiological data: 1. The juvenile form of bovine leukosis, with three different clinical forms: the multicentric, thymic, and cutaneous forms. The juvenile form is rare and shows a random geographical distribution. It has also been called sporadic bovine leukosis. 2. The ...
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Exosomes are small membranous microvesicles (40-100 nm in diameter) and are extracellularly released from a wide variety of cells. Exosomes contain microRNA, mRNA, and cellular proteins, which are delivered into recipient cells via these exosomes, and play a role in intercellular communication. In bovine leukemia virus (BLV) infection of cattle, although it is thought to be a minor route of inf...
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Enzootic bovine leukosis (EBL) is a retroviral infection that causes persistent lymphocytosis and lymphosarcoma in cattle. The economic importance of infection by bovine leukemia virus (BLV) is due to several factors, including losses in exportation, treatment of secondary infection, and reduction in dairy production. To facilitate the development of a national test that is sensitive, simple, a...
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Bovine leukemia virus (BLV) envelope glycoprotein (gp51/ gp30(T-)), consisting of BLV gp51 and BLV gp30 that lacked its C-terminal transmembrane domain, was expressed in insect cells under the control of the baculovirus polyhedron promoter. Recombinant BLV gp51/gp30(T-) secreted from insect cells was determined by immunofluorescence, enzyme-linked immunosorbent and western blot assays using a B...
متن کاملPurification of a glycoprotein from bovine leukemia virus (BLV).
A precipitating antigen of bovine leukemia virus was isolated by isoelectric focusing and Sephadex gel filtration. In SDS-polyacrylamide gel electrophoresis it was found to be a homogeneous protein with a relative molecular weight of 69000 daltons. Because of its relative molecular weight and staining characteristics it was designated as BLV gp69. A protein with the same molecular weight could ...
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ژورنال
عنوان ژورنال: The Japanese Journal of Veterinary Science
سال: 1988
ISSN: 0021-5295,1881-1442
DOI: 10.1292/jvms1939.50.1136